129 patents
Page 2 of 7
Utility
Methods of reducing or preventing oxidation of small dense LDL or membrane polyunsaturated fatty acids
20 Sep 22
In various embodiments, the present invention provides methods of treating and/or preventing cardiovascular-related disease and, in particular, a method of reducing or preventing small dense LDL (“sdLDL”) oxidation in a subject, the method comprising administering to the subject a pharmaceutical composition comprising eicosapentaenoic acid or a derivative thereof.
Richard Preston Mason
Filed: 13 Nov 18
Utility
Compositions and methods for lowering triglycerides
13 Sep 22
In various embodiments, the present invention provides compositions and methods for treating and/or preventing cardiovascular-related diseases in subject in need thereof.
Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni, Mehar Manku
Filed: 13 Jan 21
Utility
Methods of Treating Mixed Dyslipidemia
4 Aug 22
The present disclosure relates to, inter alia, methods of treating mixed dyslipidemia with ethyl eicosapentaenoate.
Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni, Mehar Manku
Filed: 20 Apr 22
Utility
Methods of treating mixed dyslipidemia
2 Aug 22
The present disclosure relates to, inter alia, methods of treating mixed dyslipidemia with ethyl eicosapentaenoate.
Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni, Mehar Manku
Filed: 1 Dec 21
Utility
Pharmaceutical Composition Comprising Eicosapentaenoic Acid and Nicotinic Acid and Methods of Using Same
9 Jun 22
The present invention relates to, inter alia, pharmaceutical compositions comprising eicosapentaenoic acid and/or derivatives thereof and nicotinic acid, to methods of manufacturing such compositions, and to therapeutic methods for treating carious diseases and disorders.
Mehar Manku
Filed: 15 Jul 21
Utility
Methods of Treating Hypercholesterolemia
12 May 22
In various embodiments, the present invention provides methods of treating and/or preventing cardiovascular-related disease and, in particular, a method of treating hypercholesterolemia, comprising administering to a subject in need thereof a pharmaceutical composition comprising eicosapentaenoic acid or a derivative thereof.
Richard Preston Mason
Filed: 19 Jan 22
Utility
Methods of treating hypertriglyceridemia
5 Apr 22
In various embodiments, the present invention provides methods of treating and/or preventing cardiovascular-related disease and, in particular, a method of blood lipid therapy comprising administering to a subject in need thereof a pharmaceutical composition comprising eicosapentaenoic acid or a derivative thereof.
Mehar Manku, Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni
Filed: 16 Mar 20
Utility
Compositions and methods for lowering triglycerides without raising LDL-C levels in a subject on concomitant statin therapy
29 Mar 22
In various embodiments, the present invention provides compositions and methods for treating and/or preventing cardiovascular-related diseases in subject in need thereof.
Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni, Mehar Manku
Filed: 10 Jun 20
Utility
Methods of Treating Mixed Dyslipidemia
17 Mar 22
The present disclosure relates to, inter alia, methods of treating mixed dyslipidemia with ethyl eicosapentaenoate.
Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni, Mehar Manku
Filed: 1 Dec 21
Utility
Methods of Treating Mixed Dyslipidemia
17 Mar 22
The present disclosure relates to, inter alia, methods of treating mixed dyslipidemia with ethyl eicosapentaenoate.
Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni, Mehar Manku
Filed: 1 Dec 21
Utility
Compositions and methods for lowering triglycerides without raising LDL-C levels in a subject on concomitant statin therapy
25 Jan 22
In various embodiments, the present invention provides compositions and methods for treating and/or preventing cardiovascular-related diseases in subject in need thereof.
Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni, Mehar Manku
Filed: 21 Nov 18
Utility
Methods of Reducing the Risk of Cardiovascular Events In a Subject
6 Jan 22
In various embodiments, the present disclosure provides methods reducing the risk of cardiovascular events in a subject on statin therapy by administering to the subject a pharmaceutical composition comprising about 1 g to about 4 g of eicosapentaenoic acid ethyl ester or a derivative thereof.
Paresh Soni
Filed: 8 Sep 21
Utility
Stable pharmaceutical composition and methods of using same
4 Jan 22
The present invention relates to, inter alia, pharmaceutical compositions comprising a polyunsaturated fatty acid and to methods of using the same to treat or prevent cardiovascular-related diseases.
Mehar Manku, Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni
Filed: 30 Dec 20
Utility
Compositions and Methods for Treating And/or Preventing Cardiovascular Disease
16 Dec 21
In various embodiments, the present invention provides pharmaceutical compositions comprising fatty acids and methods for treating subjects using same.
Jonathan Rowe
Filed: 21 Jan 21
Utility
Methods of Treating Mixed Dyslipidemia
9 Dec 21
The present disclosure relates to, inter alia, methods of treating mixed dyslipidemia with ethyl eicosapentaenoate.
Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni, Mehar Manku
Filed: 3 Aug 21
Utility
Methods of reducing apolipoprotein C-III
30 Nov 21
In various embodiments, the present invention provides methods of treating and/or preventing cardiovascular-related disease and, in particular, a method of blood lipid therapy comprising administering to a subject in need thereof a pharmaceutical composition comprising eicosapentaenoic acid or a derivative thereof.
Mehar Manku, Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni, Joseph S. Zakrzewski
Filed: 10 Feb 20
Utility
Compositions and methods for lowering triglycerides without raising LDL-C levels in a subject on concomitant statin therapy
23 Nov 21
In various embodiments, the present invention provides compositions and methods for treating and/or preventing cardiovascular-related diseases in subject in need thereof.
Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni, Mehar Manku
Filed: 3 Sep 20
Utility
Compositions and Methods for Treating or Preventing Diseases And/or Disorders Caused by Exposure to Air Pollution
28 Oct 21
In various embodiments, the present disclosure provides compositions and methods for treating and/or preventing diseases and disorders caused by exposure to air pollution and/or inhalation of particulate matter, such as oxidative stress, endothelial dysfunction, narrowing and/or thickening of arteries, and/or inflammation.
Craig Granowitz, Sephy Philip
Filed: 25 Sep 19
Utility
Methods of treating mixed dyslipidemia
26 Oct 21
The present disclosure relates to, inter alia, methods of treating mixed dyslipidemia with ethyl eicosapentaenoate.
Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni, Mehar Manku
Filed: 21 Sep 20
Utility
Stable pharmaceutical composition and methods of using same
19 Oct 21
The present invention relates to, inter alia, pharmaceutical compositions comprising a polyunsaturated fatty acid and to methods of using the same to treat or prevent cardiovascular-related diseases.
Mehar Manku, Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni
Filed: 5 Sep 19