129 patents
Page 3 of 7
Utility
Methods of treating or preventing nonalcoholic steatohepatitis and/or primary biliary cirrhosis
12 Oct 21
In various embodiments, the present invention provides methods of treating and/or preventing NASH and/or PBC comprising administering to a subject in need thereof a pharmaceutical composition comprising eicosapentaenoic acid or a derivative thereof.
Mehar Manku, Pierre Wicker, Rene Braeckman, Paresh Soni, Joseph S. Zakrzewski
Filed: 30 Nov 20
Utility
Methods of Treating And/or Preventing Viral Infections And/or Diseases Caused by Viruses In a Subject In Need Thereof
7 Oct 21
In various embodiments, the present disclosure provides methods for treating, preventing, and/or ameliorating symptoms of a viral infection, a disease, and/or a symptom thereof caused by the virus in a subject in need thereof, comprising administering about 4 g to about 20 g of icosapent ethyl to the subject per day.
Lixia Jiao, Richard Louis Dunbar, Rebecca Juliano
Filed: 7 Apr 21
Utility
Methods of reducing the risk of cardiovascular events in a subject
14 Sep 21
In various embodiments, the present disclosure provides methods reducing the risk of cardiovascular events in a subject on statin therapy by administering to the subject a pharmaceutical composition comprising about 1 g to about 4 g of eicosapentaenoic acid ethyl ester or a derivative thereof.
Paresh Soni
Filed: 20 Jan 21
Utility
Methods of reducing the risk of cardiovascular events in a subject
14 Sep 21
In various embodiments, the present disclosure provides methods reducing the risk of cardiovascular events in a subject on statin therapy by administering to the subject a pharmaceutical composition comprising about 1 g to about 4 g of eicosapentaenoic acid ethyl ester or a derivative thereof.
Paresh Soni
Filed: 2 Feb 21
Utility
Stable pharmaceutical composition and methods of using same
31 Aug 21
The present invention relates to, inter alia, pharmaceutical compositions comprising a polyunsaturated fatty acid and to methods of using the same to treat or prevent cardiovascular-related diseases.
Mehar Manku, Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni
Filed: 10 Sep 20
Utility
Compositions and Methods for Treating And/or Preventing Cardiovascular Disease
26 Aug 21
In various embodiments, the present invention provides pharmaceutical compositions comprising fatty acids and methods for treating subjects using same.
Jonathan Rowe
Filed: 19 Jan 21
Utility
Methods of Treating Hypertriglyceridemia
19 Aug 21
In various embodiments, the present invention provides methods of treating and/or preventing cardiovascular-related disease and, in particular, a method of blood lipid therapy comprising administering to a subject in need thereof a pharmaceutical composition comprising eicosapentaenoic acid or a derivative thereof.
Mehar Manku, Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni
Filed: 20 Jan 21
Utility
Methods of Treating Mixed Dyslipidemia
15 Jul 21
The present disclosure relates to, inter alia, methods of treating mixed dyslipidemia with ethyl eicosapentaenoate.
Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni, Mehar Manku
Filed: 22 Mar 21
Utility
Stable Pharmaceutical Composition and Methods of Using Same
15 Jul 21
The present invention relates to, inter alia, pharmaceutical compositions comprising a polyunsaturated fatty acid and to methods of using the same to treat or prevent cardiovascular-related diseases.
Mehar Manku, Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni
Filed: 31 Mar 21
Utility
Compositions and methods for lowering triglycerides in a subject on concomitant statin therapy and having hsCRP levels of at least about 2 mg/L
13 Jul 21
In various embodiments, the present disclosure provides compositions and methods for treating and/or preventing cardiovascular-related diseases in subject in need thereof having triglyceride levels of about 200 mg/dL to about 499 mg/dL, and hsCRP levels ≥2.0 mg/L.
Sephy Philip
Filed: 28 Feb 19
Utility
Compositions and Methods for Lowering Triglycerides
8 Jul 21
In various embodiments, the present invention provides compositions and methods for treating and/or preventing cardiovascular-related diseases in subject in need thereof.
Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni, Mehar Manku
Filed: 13 Jan 21
Utility
Compositions and Methods for Lowering Triglycerides
8 Jul 21
In various embodiments, the present invention provides compositions and methods for treating and/or preventing cardiovascular-related diseases in subject in need thereof.
Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni, Mehar Manku
Filed: 13 Jan 21
Utility
Methods of reducing RLP-C
6 Jul 21
In various embodiments, the present invention provides methods of treating and/or preventing cardiovascular-related disease and, in particular, a method of blood lipid therapy comprising administering to a subject in need thereof a pharmaceutical composition comprising eicosapentaenoic acid or a derivative thereof.
Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni, Mehar Manku
Filed: 13 Dec 19
Utility
Pharmaceutical compositions comprising EPA and a cardiovascular agent and methods of using the same
15 Jun 21
The present invention relates to, inter alia, pharmaceutical compositions comprising EPA and one or more cardiovascular agents, and to therapeutic methods for treating various diseases and disorders using the same.
Mehar Manku, Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni
Filed: 29 Apr 10
Utility
Methods of Reducing the Risk of Cardiovascular Events In a Subject
27 May 21
In various embodiments, the present disclosure provides methods reducing the risk of cardiovascular events in a subject on statin therapy by administering to the subject a pharmaceutical composition comprising about 1 g to about 4 g of eicosapentaenoic acid ethyl ester or a derivative thereof.
Paresh Soni
Filed: 2 Feb 21
Utility
Methods of Treating or Preventing Prostate Cancer
20 May 21
In various embodiments, the present invention provides methods of treating and/or preventing prostate cancer and, in particular, the method comprising administering to a subject in need thereof a pharmaceutical composition comprising eicosapentaenoic acid or a derivative thereof.
Joseph S. Zakrzewski
Filed: 22 Oct 20
Utility
Methods of Reducing Apolipoprotein C-iii
20 May 21
In various embodiments, the present invention provides methods of treating and/or preventing cardiovascular-related disease and, in particular, a method of blood lipid therapy comprising administering to a subject in need thereof a pharmaceutical composition comprising eicosapentaenoic acid or a derivative thereof.
Mehar Manku, Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni, Joseph S. Zakrzewski
Filed: 23 Nov 20
Utility
Pharmaceutical composition comprising omega-3 fatty acid and hydroxy-derivative of a statin and methods of using same
18 May 21
In various embodiments, the present invention provides compositions and methods for treating and/or preventing a cardiovascular-related disease in subject in need thereof.
Jonathan Rowe
Filed: 15 Oct 19
Utility
Compositions and Methods for Lowering Triglycerides in a Subject Having Reduced Kidney Function
13 May 21
In various embodiments, the present invention provides compositions and methods for treating and/or preventing cardiovascular-related diseases in subject having reduced kidney function.
Sephy Philip
Filed: 12 Jan 21
Utility
Methods of Reducing the Risk of Cardiovascular Events In a Subject
13 May 21
In various embodiments, the present disclosure provides methods reducing the risk of cardiovascular events in a subject on statin therapy by administering to the subject a pharmaceutical composition comprising about 1 g to about 4 g of eicosapentaenoic acid ethyl ester or a derivative thereof.
Paresh Soni
Filed: 20 Jan 21