129 patents
Page 5 of 7
Utility
Methods of reducing the risk of a cardiovascular event in a subject at risk for cardiovascular disease
19 Jan 21
In various embodiments, the present invention provides methods of reducing the risk of a cardiovascular event in a subject on statin therapy and, in particular, a method of reducing the risk of a cardiovascular event in a subject on statin therapy having a fasting baseline triglyceride level of about 135 mg/dL to about 500 mg/dL, and administering to the subject a pharmaceutical composition comprising about 1 g to about 4 g of eicosapentaenoic acid ethyl ester or a derivative thereof.
Paresh Soni
Filed: 29 Jan 20
Utility
Pharmaceutical compositions comprising omega-3 fatty acids
12 Jan 21
The present disclosure relates to, inter alia, pharmaceutical compositions comprising omega-3 fatty acids.
Mehar Manku, Jonathan Rowe
Filed: 7 Nov 14
Utility
Methods of treating or preventing prostate cancer
12 Jan 21
In various embodiments, the present invention provides methods of treating and/or preventing prostate cancer and, in particular, the method comprising administering to a subject in need thereof a pharmaceutical composition comprising eicosapentaenoic acid or a derivative thereof.
Joseph S. Zakrzewski
Filed: 13 Sep 17
Utility
Methods of Treating Mixed Dyslipidemia
6 Jan 21
The present disclosure relates to, inter alia, methods of treating mixed dyslipidemia with ethyl eicosapentaenoate.
Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni, Mehar Manku
Filed: 20 Sep 20
Utility
Stable pharmaceutical composition and methods of using same
4 Jan 21
The present invention relates to, inter alia, pharmaceutical compositions comprising a polyunsaturated fatty acid and to methods of using the same to treat or prevent cardiovascular-related diseases.
Mehar Manku, Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni
Filed: 4 Jun 20
Utility
Stable Pharmaceutical Composition and Methods of Using Same
30 Dec 20
The present invention relates to, inter alia, pharmaceutical compositions comprising a polyunsaturated fatty acid and to methods of using the same to treat or prevent cardiovascular-related diseases.
Mehar Manku, Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni
Filed: 9 Sep 20
Utility
Compositions and Methods for Lowering Triglycerides Without Raising LDL-C Levels in a Subject on Concomitant Statin Therapy
30 Dec 20
In various embodiments, the present invention provides compositions and methods for treating and/or preventing cardiovascular-related diseases in subject in need thereof.
Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni, Mehar Manku
Filed: 9 Jun 20
Utility
Compositions and Methods for Lowering Triglycerides without Raising LDL-C Levels in a Subject on Concomitant Statin Therapy
23 Dec 20
In various embodiments, the present invention provides compositions and methods for treating and/or preventing cardiovascular-related diseases in subject in need thereof.
Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni, Mehar Manku
Filed: 2 Sep 20
Utility
Compositions comprising eicosapentaenoic acid and mipomersen and methods of use thereof
30 Nov 20
The present invention relates to, inter alia, pharmaceutical compositions comprising a polyunsaturated fatty acid and to methods of using the same to treat or prevent cardiovascular-related diseases.
Joseph S. Zakrzewski
Filed: 12 Nov 18
Utility
Stable pharmaceutical composition and methods of using same
23 Nov 20
The present invention relates to, inter alia, pharmaceutical compositions comprising a polyunsaturated fatty acid and to methods of using the same to treat or prevent cardiovascular-related diseases.
Mehar Manku, Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni
Filed: 25 Nov 19
Utility
Compositions and methods for lowering triglycerides
23 Nov 20
In various embodiments, the present invention provides compositions and methods for treating and/or preventing cardiovascular-related diseases in subject in need thereof.
Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni, Mehar Manku
Filed: 25 Mar 19
Utility
Methods of reducing or preventing oxidation of small dense ldl or membrane polyunsaturated fatty acids
23 Nov 20
In various embodiments, the present invention provides methods of treating and/or preventing cardiovascular-related disease and, in particular, a method of reducing or preventing sdLDL oxidation in a subject, the method comprising administering to the subject a pharmaceutical composition comprising eicosapentaenoic acid or a derivative thereof.
Richard Preston Mason
Filed: 27 Jun 19
Utility
Methods of Reducing the Risk of Cardiovascular Events In a Subject
28 Oct 20
In various embodiments, the present disclosure provides methods reducing the risk of cardiovascular events in a subject on statin therapy by administering to the subject a pharmaceutical composition comprising about 1 g to about 4 g of eicosapentaenoic acid ethyl ester or a derivative thereof.
Paresh Soni
Filed: 12 Jul 20
Utility
Methods of Reducing Apolipoprotein C-III
7 Oct 20
In various embodiments, the present invention provides methods of treating and/or preventing cardiovascular-related disease and, in particular, a method of blood lipid therapy comprising administering to a subject in need thereof a pharmaceutical composition comprising eicosapentaenoic acid or a derivative thereof.
Mehar Manku, Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni, Joseph S. Zakrzewski
Filed: 9 Feb 20
Utility
Methods of reducing the risk of a cardiovascular event in a subject at risk for cardiovascular disease
5 Oct 20
In various embodiments, the present invention provides methods of reducing the risk of a cardiovascular event in a subject on statin therapy and, in particular, a method of reducing the risk of a cardiovascular event in a subject on statin therapy having a fasting baseline triglyceride level of about 135 mg/dL to about 500 mg/dL, and administering to the subject a pharmaceutical composition comprising about 1 g to about 4 g of eicosapentaenoic acid ethyl ester or a derivative thereof.
Paresh Soni
Filed: 28 Jul 19
Utility
Methods of treating mixed dyslipidemia
5 Oct 20
The present disclosure relates to, inter alia, methods of treating cardiovascular-related disease.
Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni, Mehar Manku
Filed: 18 Apr 19
Utility
Methods of reducing the risk of cardiovascular events in a subject
28 Sep 20
In various embodiments, the present disclosure provides methods reducing the risk of cardiovascular events in a subject on statin therapy by administering to the subject a pharmaceutical composition comprising about 1 g to about 4 g of eicosapentaenoic acid ethyl ester or a derivative thereof.
Paresh Soni
Filed: 7 Jan 20
Utility
Stable Pharmaceutical Composition and Methods of Using Same
23 Sep 20
The present invention relates to, inter alia, pharmaceutical compositions comprising a polyunsaturated fatty acid and to methods of using the same to treat or prevent cardiovascular-related diseases.
Mehar Manku, Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni
Filed: 4 Jun 20
Utility
Low Eructation Composition and Methods for Treating And/or Preventing Cardiovascular Disease In a Subject with Fish Allergy/hypersensitivity
23 Sep 20
In various embodiments, the present invention provides pharmaceutical compositions and methods for treating cardiovascular-related disease.
Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni, Jonathan Rowe
Filed: 2 Dec 19
Utility
Compositions and Methods for Treating And/or Preventing Cardiovascular Disease
23 Sep 20
In various embodiments, the present invention provides pharmaceutical compositions comprising fatty acids and methods for treating subjects using same.
Jonathan Rowe
Filed: 5 May 19