129 patents
Page 6 of 7
Utility
Methods of Reducing or Preventing Oxidative Modification of Membrane Polyunsaturated Fatty Acids
16 Sep 20
In various embodiments, the present invention provides methods of treating and/or preventing cardiovascular-related disease and, in particular, a method of reducing or preventing membrane cholesterol domain formation in a subject, the method comprising administering to a subject in need thereof a pharmaceutical composition comprising eicosapentaenoic acid or a derivative thereof.
Richard Preston Mason
Filed: 28 May 20
Utility
Methods of Treating Hypertriglyceridemia
26 Aug 20
In various embodiments, the present invention provides methods of treating and/or preventing cardiovascular-related disease and, in particular, a method of blood lipid therapy comprising administering to a subject in need thereof a pharmaceutical composition comprising eicosapentaenoic acid or a derivative thereof.
Rene Braeckman, William Stirtan, Paresh Soni
Filed: 17 Feb 20
Utility
Methods of Reducing the Risk of a Cardiovascular Event In a Statin-treated Subject by Increasing Serum and Plasma Epa and Dpa Levels
19 Aug 20
In various embodiments, the present disclosure provides methods reducing the risk of a cardiovascular event in a subject on statin therapy by administering to the subject a pharmaceutical composition comprising about 1 g to about 4 g of eicosapentaenoic acid ethyl ester or a derivative thereof by increasing the subject's plasma and serum EPA levels.
Paresh Soni, Mehar Manku
Filed: 13 Feb 20
Utility
Methods of Treating Hypertriglyceridemia
5 Aug 20
In various embodiments, the present invention provides methods of treating and/or preventing cardiovascular-related disease and, in particular, a method of blood lipid therapy comprising administering to a subject in need thereof a pharmaceutical composition comprising eicosapentaenoic acid or a derivative thereof.
Mehar Manku, Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni
Filed: 20 Apr 20
Utility
Methods of Reducing or Preventing Oxidation of Small Dense LDL or Membrane Polyunsaturated Fatty Acids
29 Jul 20
In various embodiments, the present invention provides methods of treating and/or preventing cardiovascular-related disease and, in particular, a method of reducing or preventing sdLDL oxidation in a subject, the method comprising administering to the subject a pharmaceutical composition comprising eicosapentaenoic acid or a derivative thereof.
Richard Preston Mason
Filed: 12 Apr 20
Utility
Methods of Reducing or Preventing Oxidative Modification of Membrane Polyunsaturated Fatty Acids
29 Jul 20
In various embodiments, the present invention provides methods of treating and/or preventing cardiovascular-related disease and, in particular, a method of reducing or preventing membrane cholesterol domain formation in a subject, the method comprising administering to a subject in need thereof a pharmaceutical composition comprising eicosapentaenoic acid or a derivative thereof.
Richard Preston Mason
Filed: 12 Apr 20
Utility
Compositions and methods for lowering triglycerides without raising LDL-C levels in a subject on concomitant statin therapy
27 Jul 20
In various embodiments, the present invention provides compositions and methods for treating and/or preventing cardiovascular-related diseases in subject in need thereof.
Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni, Mehar Manku
Filed: 14 Apr 19
Utility
Methods of Treating Hypertriglyceridemia
8 Jul 20
In various embodiments, the present invention provides methods of treating and/or preventing cardiovascular-related disease and, in particular, a method of blood lipid therapy comprising administering to a subject in need thereof a pharmaceutical composition comprising eicosapentaenoic acid or a derivative thereof.
Mehar Manku, Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni
Filed: 15 Mar 20
Utility
Methods of Reducing Apolipoprotein C-iii
24 Jun 20
In various embodiments, the present invention provides methods of treating and/or preventing cardiovascular-related disease and, in particular, a method of blood lipid therapy comprising administering to a subject in need thereof a pharmaceutical composition comprising eicosapentaenoic acid or a derivative thereof.
Mehar Manku, Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni, Joseph S. Zakrzewski
Filed: 26 Feb 20
Utility
Compositions and Methods for Lowering Triglycerides
17 Jun 20
In various embodiments, the present invention provides compositions and methods for treating and/or preventing cardiovascular-related diseases in subject in need thereof.
Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni, Mehar Manku
Filed: 19 Feb 20
Utility
Compositions and Methods for Lowering Triglycerides
17 Jun 20
In various embodiments, the present invention provides compositions and methods for treating and/or preventing cardiovascular-related diseases in subject in need thereof.
Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni, Mehar Manku
Filed: 19 Feb 20
Utility
Methods of reducing apolipoprotein C-III
8 Jun 20
In various embodiments, the present invention provides methods of treating and/or preventing cardiovascular-related disease and, in particular, a method of blood lipid therapy comprising administering to a subject in need thereof a pharmaceutical composition comprising eicosapentaenoic acid or a derivative thereof.
Mehar Manku, Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni, Joseph S. Zakrzewski
Filed: 13 Nov 18
Utility
Methods of reducing the risk of cardiovascular events in a subject
1 Jun 20
In various embodiments, the present disclosure provides methods reducing the risk of cardiovascular events in a subject on statin therapy by administering to the subject a pharmaceutical composition comprising about 1 g to about 4 g of eicosapentaenoic acid ethyl ester or a derivative thereof.
Paresh Soni
Filed: 21 Apr 19
Utility
Methods of Reducing the Risk of a Cardiovascular Event In a Subject at Risk for Cardiovascular Disease
27 May 20
In various embodiments, the present invention provides methods of reducing the risk of a cardiovascular event in a subject on statin therapy and, in particular, a method of reducing the risk of a cardiovascular event in a subject on statin therapy having a fasting baseline triglyceride level of about 135 mg/dL to about 500 mg/dL, and administering to the subject a pharmaceutical composition comprising about 1 g to about 4 g of eicosapentaenoic acid ethyl ester or a derivative thereof.
Paresh Soni
Filed: 28 Jan 20
Utility
Methods of Reducing the Risk of Cardiovascular Events In a Subject
6 May 20
In various embodiments, the present disclosure provides methods reducing the risk of cardiovascular events in a subject on statin therapy by administering to the subject a pharmaceutical composition comprising about 1 g to about 4 g of eicosapentaenoic acid ethyl ester or a derivative thereof.
Paresh Soni
Filed: 7 Jan 20
Utility
Methods of treating hypertriglyceridemia
27 Apr 20
In various embodiments, the present invention provides methods of treating and/or preventing cardiovascular-related disease and, in particular, a method of blood lipid therapy comprising administering to a subject in need thereof a pharmaceutical composition comprising eicosapentaenoic acid or a derivative thereof.
Mehar Manku, Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni
Filed: 9 Jun 19
Utility
Methods of Treating Mixed Dyslipidemia
22 Apr 20
The present disclosure relates to, inter alia, methods of treating mixed dyslipidemia with ethyl eicosapentaenoate.
Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni, Mehar Manku
Filed: 9 Dec 19
Utility
Methods of Reducing RLP-C
22 Apr 20
In various embodiments, the present invention provides methods of treating and/or preventing cardiovascular-related disease and, in particular, a method of blood lipid therapy comprising administering to a subject in need thereof a pharmaceutical composition comprising eicosapentaenoic acid or a derivative thereof.
Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni, Mehar Manku
Filed: 12 Dec 19
Utility
Methods of treating mixed dyslipidemia
20 Apr 20
The present disclosure relates to, inter alia, methods of treating cardiovascular-related disease.
Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni, Mehar Manku
Filed: 24 Feb 19
Utility
Stable Pharmaceutical Composition and Methods of Using Same
15 Apr 20
The present invention relates to, inter alia, pharmaceutical compositions comprising a polyunsaturated fatty acid and to methods of using the same to treat or prevent cardiovascular-related diseases.
Mehar Manku, Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni
Filed: 25 Nov 19