117 patents
Page 4 of 6
Utility
Heat-stable Dry Powder Pharmaceutical Compositions and Methods
12 Aug 21
Disclosed herein are heat-stable dry powders which include peptides or protein such as oxytocin for use as a pharmaceutical composition.
Karine Fabio, Joseph J. Guarneri, Kieran Curley, Marshall L. Grant, Andrea Leone-Bay
Filed: 27 Apr 21
Utility
Use of Ultrarapid Acting Insulin
12 Aug 21
Disclosed herein are improved methods of treating hyperglycemia with a combination of an ultrarapid acting insulin and insulin glargine comprising prandial administration of the ultrarapid insulin, and administration of a first dose of insulin glargine within 6 hours of waking for a day.
Anders Hasager Boss, Richard Petrucci
Filed: 26 Apr 21
Utility
Dry Powder Drug Delivery System
12 Aug 21
A pulmonary drug delivery system is disclosed, including a breath-powered, dry powder inhaler, and a cartridge for delivering a dry powder formulation.
Chad C. Smutney, Benoit Adamo, John M. Polidoro, P. Spencer Kinsey, Dennis Overfield, Carl R. Sahi, Christine Billings, Mark T. Marino
Filed: 29 Apr 21
Utility
Apparatus and method for cryogranulating a pharmaceutical composition
3 Aug 21
Cryogranulation systems with improved dispenser assemblies are provided for use in manufacturing frozen pellets of pharmaceutical substances in a fluid medium.
Edwin Amoro, Karel Vanackere, Michael A. White
Filed: 6 Nov 19
Utility
Heat-stable dry powder pharmaceutical compositions and methods
25 May 21
Disclosed herein are heat-stable dry powders which include peptides or protein such as oxytocin for use as a pharmaceutical composition.
Karine Fabio, Joseph J. Guarneri, Kieran Curley, Marshall L. Grant, Andrea Leone-Bay
Filed: 1 Aug 19
Utility
Method of drug formulation based on increasing the affinity of crystalline microparticle surfaces for active agents
25 May 21
Methods are provided for coating crystalline microparticles with an active agent by altering the surface properties of the microparticles in order to facilitate favorable association on the microparticle by the active agent.
Keith A. Oberg, Joseph Sulner, Marshall L. Grant
Filed: 12 Jun 19
Utility
Use of ultrarapid acting insulin
25 May 21
Disclosed herein are improved methods of treating hyperglycemia with a combination of an ultrarapid acting insulin and insulin glargine comprising prandial administration of the ultrarapid insulin, and administration of a first dose of insulin glargine within 6 hours of waking for a day.
Anders Hasager Boss, Richard Petrucci
Filed: 16 Apr 19
Utility
Dry Powder Inhaler
20 May 21
A dry powder inhaler including replaceable cartridges containing a dry powder for local or systemic delivery through the pulmonary tract and lungs is disclosed.
P. Spencer Kinsey, Brendan Laurenzi, Chad C. Smutney, Benoit Adamo, Joseph Guarneri, John J. Freeman, JR.
Filed: 26 Jan 21
Utility
Method of Treating Diabetes Type 2 by Administering Ultrarapid Acting Insulin
13 May 21
Disclosed herein are improved methods of treating hyperglycemia with a combination of an ultrarapid acting insulin and insulin glargine comprising prandial administration of the ultrarapid insulin, and administration of a first dose of insulin glargine within 6 hours of waking for a day.
Peter Richardson, Robert A. Baughman, Elizabeth Potocka, Anders Hasager Boss, Richard Petrucci
Filed: 25 Nov 20
Utility
Diketopiperazine salts for drug delivery and related methods
13 May 21
Drug delivery systems have been developed based on the formation of diketopiperazine carboxylate salts and microparticles containing the same.
Andrea Leone-Bay, Destardi Moye-Sherman, Bryan R. Wilson
Filed: 5 Jan 21
Utility
Methods for the synthesis of activated ethylfumarates and their use as intermediates
22 Apr 21
Disclosed embodiments relate to improved methods for the synthesis of activated fumarate intermediates and their use in chemical synthesis.
Kelly Sullivan Kraft, John J. Freeman, Paul Serwinski, Vincent Pavia, Otto Phanstiel, Navneet Kaur
Filed: 7 Dec 20
Utility
Diketopiperazine salts for drug delivery and related methods
9 Feb 21
Drug delivery systems have been developed based on the formation of diketopiperazine carboxylate salts and microparticles containing the same.
Andrea Leone-Bay, Destardi Moye-Sherman, Bryan R. Wilson
Filed: 27 Jan 20
Utility
Method and Composition for Administering Prostaglandins
30 Dec 20
A method for treating migraines is disclosed.
Joseph J. Guarneri, Marshall Grant, Chad C. Smutney, John J. Freeman, JR., Nikhil Amin, Kelly S. Kraft, Andrea Leone-Bay
Filed: 8 Sep 20
Utility
Use of Ultrarapid Acting Insulin
23 Dec 20
Disclosed herein are improved methods of treating hyperglycemia with a combination of an ultrarapid acting insulin and insulin glargine comprising prandial administration of the ultrarapid insulin, and administration of a first dose of insulin glargine within 6 hours of waking for a day.
Anders Hasager Boss, Richard Petrucci, Campbell Howard, Alfred Mann
Filed: 13 Aug 20
Utility
Formation of N-protected 3,6-bis-(4-aminobutyl)-2,5-diketopiperazine through a cyclic α-N-protected amino ester
21 Dec 20
A method for the synthesis of N-protected 3,6-aminoalkyl-2,5-diketopiperazines is provided.
John J. Freeman, Otto Phanstiel, William Elliot Bay, Kelly Sullivan Kraft
Filed: 1 Mar 20
Utility
Method of treating diabetes type 2 by administering ultrarapid acting insulin
7 Dec 20
Disclosed herein are improved methods of treating hyperglycemia with a combination of an ultrarapid acting insulin and insulin glargine comprising prandial administration of the ultrarapid insulin, and administration of a first dose of insulin glargine within 6 hours of waking for a day.
Peter Richardson, Robert A. Baughman, Elizabeth Potocka, Anders Hasager Boss, Richard Petrucci
Filed: 1 Mar 18
Utility
Methods for the synthesis of activated ethylfumarates and their use as intermediates
7 Dec 20
Disclosed embodiments relate to improved methods for the synthesis of activated fumarate intermediates and their use in chemical synthesis.
Kelly Sullivan Kraft, John J. Freeman, Paul Serwinski, Vincent Pavia, Otto Phanstiel, Navneet Kaur
Filed: 9 Sep 18
Utility
Diketopiperazine Microparticles with Defined Specific Surface Areas
2 Dec 20
Disclosed herein are diketopiperazine microparticles having a specific surface area of less than about 67 m2/g.
Marshall L. Grant, Grayson W. Stowell, Paul Menkin, John J. Freeman, JR.
Filed: 13 Aug 20
Utility
Dry Powder Inhaler and System for Drug Delivery
4 Nov 20
A breath-powered, dry powder inhaler, a cartridge, and a pulmonary drug delivery system are provided.
Chad C. Smutney, P. Spencer Kinsey, Carl R. Sahi, Benoit Adamo, John M. Polidoro
Filed: 16 Jul 20
Utility
Dry Powder Drug Delivery System and Methods
28 Oct 20
A pulmonary drug delivery system is disclosed, including a breath-powered, dry powder inhaler, with or without a cartridge for delivering a dry powder formulation.
Chad C. Smutney, Benoit Adamo, Brendan F. Laurenzi, P. Spencer Kinsey
Filed: 7 Jul 20