15 patents
Utility
Method of using biomarkers and clinical variables for predicting chemotherapy benefit
22 Nov 22
Provided herein are methods for predicting chemotherapy benefit.
Alexander Gutin, Julia Reid, Ralf Kronenwett, Marsel Scheer
Filed: 4 Mar 20
Utility
Copy number variant caller
25 Jan 22
Direct targeted sequencing (DTS) methods and a hidden Markov model (HMM) can be used to call the copy number of a segment of interest within a region of interest.
Kevin R. Haas, Xin Wang, Peter V. Grauman
Filed: 23 Mar 18
Utility
Methods and materials for assessing allelic imbalance
18 Jan 22
Methods and systems for detecting allelic imbalance using nucleic acid sequencing are provided.
Alexander Gutin, Kirsten Timms, Jerry Lanchbury
Filed: 11 Mar 20
Utility
Gene signatures for cancer prognosis
16 Nov 21
Biomarkers and methods using the biomarkers for classifying cancer in a patient (e.g., predicting the risk of cancer-specific death or cancer recurrence) are provided.
Steven Stone, Alexander Gutin, Julia Reid
Filed: 11 Nov 16
Utility
Method of treating cancer
16 Nov 21
This document provides methods and materials involved in assessing samples (e.g., cancer cells) for the presence of a loss of heterozygosity (LOH) signature.
Victor Abkevich, Alexander Gutin, Kirsten Timms, Jerry Lanchbury
Filed: 21 Nov 19
Utility
Hereditary cancer genes
31 Aug 21
The invention generally relates to a molecular classification of disease predisposition and particularly to molecular markers for cancer predisposition and methods of use thereof.
Kirsten Timms, Brian Allen, Anne-Renee Hartman
Filed: 5 Dec 14
Utility
Genes and gene signatures for diagnosis and treatment of melanoma
1 Jun 21
Panels of biomarkers, methods and systems are disclosed for determining gene expression, and diagnosing and treating melanoma.
Michael Bryan Warf, Benjamin Roa, Alexander Gutin, Darl Flake
Filed: 12 Mar 14
Utility
Gene signatures for cancer prognosis
23 Mar 21
Biomarkers and methods using the biomarkers for the prediction of the recurrence risk of cancer in a patient are provided.
Steven Stone, Alexander Gutin, Susanne Wagner, Julia E. Reid
Filed: 26 Feb 15
Utility
Gene signatures for cancer prognosis
28 Dec 20
Biomarkers and methods using the biomarkers for classifying cancer in a patient (e.g., predicting the risk of cancer-specific death or cancer recurrence) are provided.
Steven Stone, Alexander Gutin, Susanne Wagner, Julia Reid
Filed: 14 May 15
Utility
Method for treating cancer
30 Nov 20
This document provides methods and materials involved in assessing samples (e.g., cancer cells) for the presence of a loss of heterozygosity (LOH) signature.
Victor Abkevich, Alexander Gutin, Kirsten Timms, Jerry Lanchbury
Filed: 18 Sep 19
Utility
Methods and materials for assessing allelic imbalance
20 Apr 20
Methods and systems for detecting allelic imbalance using nucleic acid sequencing are provided.
Alexander Gutin, Kirsten Timms, Jerry Lanchbury
Filed: 22 Jan 17
Utility
Methods and materials for assessing loss of heterozygosity
6 Apr 20
This document provides methods and materials involved in assessing samples (e.g., cancer cells) for the presence of a loss of heterozygosity (LOH) signature.
Victor Abkevich, Alexander Gutin, Kirsten Timms, Jerry Lanchbury
Filed: 23 Jun 16
Utility
Genes and gene signatures for diagnosis and treatment of melanoma
6 Apr 20
Panels of biomarkers, methods and systems are disclosed for determining gene expression, and diagnosing and treating melanoma.
Michael Bryan Warf, Benjamin Roa, Alexander Gutin, Darl Flake
Filed: 21 Dec 16
Utility
Cancer Biomarkers
30 Dec 19
Biomarkers and methods using the biomarkers for the prediction of the recurrence risk of cancer in a patient are provided.
Steven Stone, Alexander Gutin, Susanne Wagner, Julia Reid
Filed: 23 Jan 19
Utility
Cancer biomarkers
9 Dec 19
Biomarkers and methods using the biomarkers for the prediction of the recurrence risk of cancer in a patient are provided.
Steven Stone, Alexander Gutin, Susanne Wagner, Julia Reid
Filed: 12 Mar 18
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