13 patents
Utility
Compositions for cancer therapy and methods
14 Nov 23
One aspect of this disclosure is directed to a method for treating a cancer in a subject in need thereof by administering to the subject at least a first compound and a second compound together or separately.
David R. Strayer, Thomas K. Equels
Filed: 9 Aug 19
Utility
Methods for improving exercise tolerance in myalgic encephalomyelitis patients
14 Nov 23
The present invention relates to methods for treating a subject with myalgic encephalomyelitis/chronic fatigue syndrome symptoms comprising administering a target subject a pharmaceutical composition comprising a therapeutic dsRNA (tdsRNA).
David R. Strayer, Diane L. Young, Thomas K. Equels
Filed: 25 Nov 19
Utility
Method of reducing antigenic drift or reassortment of viruses in a host animal using α interferon
9 May 23
This disclosures relates to methods of preventing or reducing antigenic drift, viral reassortment and symptoms of wild-type and mutant influenza viruses in a host animal by determining if a host animal has been exposed to or infected by an avian influenza virus, and administering to the exposed host animal α-interferon.
William A. Carter, David R. Strayer
Filed: 21 Aug 14
Utility
Compositions and Methods for Treating Cancer
8 Dec 22
Disclosed is a method for treating a cancer, such as pancreatic cancer, in a subject.
Thomas K. EQUELS, David R. STRAYER
Filed: 21 Sep 21
Utility
Methods and Compositions for Treating Endometriosis
8 Dec 22
Disclosed is a method for treating endometriosis, preventing endometriosis, or ameliorating a symptom of endometriosis in a subject comprising the step of administering to the subject a therapeutically effective amount of a pharmaceutical composition comprising as an active ingredient a therapeutic dsRNA (tdsRNA).
Thomas K. EQUELS, David R. STRAYER
Filed: 22 Oct 20
Utility
Therapeutic Double Stranded Rna and Methods for Producing the Same
8 Dec 22
Disclosed is a method for the synthesis of a therapeutic double-stranded RNA (tdsRNA), comprising: a) synthesizing a first single-stranded RNA (first ssRNA) in a first synthesis reaction with PNPase as the only RNA polymerase; b) synthesizing a second single-stranded RNA (second ssRNA) in a second synthesis reaction with PNPase as the only RNA polymerase; and c) hybridizing the first ssRNA with the second ssRNA to form the tdsRNA; wherein step a) and step b) are performed in any order.
Thomas K. EQUELS, Vishwajeetsinh M. ATODARIA, Victoria G. SCOTT, David R. STRAYER, Peter W. RODINO
Filed: 25 Jan 21
Utility
Methods, Compositions, and Vaccines for Treating a Virus Infection
1 Dec 22
This disclosure relates to a method of treating, preventing, or reducing a symptom of a virus infection, including a SARS-CoV-2 infection, by administering an effective amount of tdsRNA optionally with an anti-viral agent, to a subject.
Thomas K. EQUELS, David R. STRAYER, Diane L. YOUNG
Filed: 25 Jan 21
Utility
Compositions and Methods Useful for Ebola Virus Infection
10 Nov 22
Disclosed are methods and compositions for at least preventing, treating, inhibiting, or attenuating an Ebola virus infection of a subject.
David R. STRAYER, Thomas K. EQUELS
Filed: 2 Jul 20
Utility
Compositions and Methods for Treating Long Covid
8 Sep 22
This disclosure relates to compositions and methods for treating a subject previously infected with a virus and afflicted with post viral fatigue symptoms such as, for example, Long Covid.
Thomas K. EQUELS, David R. STRAYER, Diane L. YOUNG
Filed: 16 May 22
Utility
Compositions and Methods for Cancer Therapy
31 Mar 22
One aspect of this disclosure is directed to a method for treating a cancer in a subject in need thereof by administering to the subject at least a first compound and a second compound in any order together or separately.
David R. STRAYER, Thomas K. EQUELS
Filed: 20 Dec 19
Utility
Methods for Improving Exercise Tolerance In Myalgic Encephalomyelitis Patients
3 Mar 22
The present invention relates to methods for treating a subject with myalgic encephalomyelitis/chronic fatigue syndrome symptoms comprising administering a target subject a pharmaceutical composition comprising a therapeutic dsRNA (tdsRNA).
David R. STRAYER, Diane L. YOUNG, Thomas K. EQUELS
Filed: 25 Nov 19
Utility
Compositions for Cancer Therapy and Methods
1 Jul 21
One aspect of this disclosure is directed to a method for treating a cancer in a subject in need thereof by administering to the subject at least a first compound and a second compound together or separately.
David R. STRAYER, Thomas K. EQUELS
Filed: 18 Feb 21
Utility
Compositions for Cancer Therapy and Methods
24 Jun 20
One aspect of this disclosure is directed to a method for treating a cancer in a subject in need thereof by administering to the subject at least a first compound and a second compound together or separately.
David R. STRAYER, Thomas K. EQUELS
Filed: 8 Aug 19
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