|Allison Wey||Vice President of Investor Relations and Corporate Communications|
|Jay Hagan||President, Chief Executive Officer, Principal Executive Officer, Director|
|Tim Wright||Chief Research and Development Officer|
|Dan Chevallard||Chief Financial Officer, Principal Financial and Accounting Officer|
|Matthew Luchini||BMO Capital|
|Joseph Thome||Cowen and Company|
|Nick Abbott||Wells Fargo|
Good afternoon. My name is Sonya and I will be your conference operator today. At this time, I would like to welcome everyone to the Regulus Therapeutics third quarter 2017 conference call. All lines have been placed on mute to prevent any background noise. After the speakers' remarks, there will be a question-and-answer session.