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Eloxx Pharmaceuticals (ELOX)

Utility
Aminoglycoside derivatives and uses thereof in treating genetic disorders
19 Apr 22
Novel pseudo-disaccharide and pseudo-trisaccharide aminoglycosides, represented by Formulae I or Ia, as defined in the instant specification, designed to exhibit stop codon mutation readthrough activity, are provided.
Timor Baasov
Filed: 2 Sep 16
Utility
Methods, Compositions, and Kits for Treating Ocular Diseases
13 Jan 22
Provided herein are methods of treating an ocular disease associated with one or more nonsense mutation in a subject using one or more amino-glycosides and/or derivatives thereof.
John VAN DUZER, Greg WILLIAMS
Filed: 27 Nov 19
Utility
Large scale preparation of pseudo-trisaccharide aminoglycosides and of intermediates thereof
5 Oct 21
Synthetic pathways for preparing pseudo-trisaccharide aminoglycoside compounds represented by Formula I or Ia as defined in the specification and donor and acceptor compounds useful for preparing such compounds are provided.
Michael Mizhiritskii, Mani Bushan Kotala, Ravinder Palidi
Filed: 15 Mar 18
Utility
Aminoglycoside Derivatives and Uses Thereof In Treating Genetic Disorders
30 Sep 21
Novel aminoglycosides, represented by Formulae Ia and Ib, as defined in the instant specification, designed to exhibit stop codon mutation readthrough activity, are provided.
Timor BAASOV, Shmuel TUVIA
Filed: 17 Dec 20
Utility
Aminoglycoside Derivatives and Uses Thereof In Treating Genetic Disorders
22 Jul 21
Novel pseudo-trisaccharide aminoglycosides, represented by Formula I, as defined in the instant specification, designed to exhibit stop codon mutation readthrough activity, are provided.
Timor Baasov
Filed: 25 Sep 20
Utility
Aminoglycoside derivatives and uses thereof in treating genetic disorders
26 Jan 21
Novel aminoglycosides, represented by Formulae Ia and Ib, as defined in the instant specification, designed to exhibit stop codon mutation readthrough activity, are provided.
Timor Baasov, Shmuel Tuvia
Filed: 2 Sep 16
Utility
Aminoglycoside derivatives and uses thereof in treating genetic disorders
28 Sep 20
Novel pseudo-trisaccharide aminoglycosides, represented by Formula I, as defined in the instant specification, designed to exhibit stop codon mutation readthrough activity, are provided.
Timor Baasov
Filed: 1 Sep 16
Utility
Large Scale Preparation of Pseudo-trisaccharide Aminoglycosides and of Intermediates Thereof
11 Mar 20
Synthetic pathways for preparing pseudo-trisaccharide aminoglycoside compounds represented by Formula I or Ia as defined in the specification and donor and acceptor compounds useful for preparing such compounds are provided.
Michael MIZHIRITSKII, Mani Bushan KOTALA, Ravinder PALIDI
Filed: 14 Mar 18
Utility
Use of aminoglycoside analogs in the treatment of Rett syndrome
2 Mar 20
Timor Baasov, Shmuel Tuvia, Dori Pelled
Filed: 27 Jan 19
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