121 patents
Page 6 of 7
Utility
Optimizing mifepristone levels for cushing's patients
25 May 20
The present invention provides a method for optimizing levels of mifepristone in a patient suffering from Cushing's syndrome.
Joseph Belanoff, Coleman Gross
Filed: 12 Dec 18
Utility
Methods for Shrinking Pituitary Tumors
13 May 20
Andreas Moraitis
Filed: 7 Nov 19
Utility
Glucocorticoid Receptor Modulators to Treat Cervical Cancer
13 May 20
Methods for treating a subject having a cancerous tumor are disclosed.
Hazel Hunt
Filed: 13 Jan 20
Utility
Methods of Treating Neuroepithelial Tumors Using Selective Glucocorticoid Receptor Modulators
13 May 20
Applicant discloses methods for treating a glucocorticoid receptor positive (GR+) neuroepithelial tumor in a subject, comprising administering a selective glucocorticoid receptor modulator (SGRM) in an amount effective to reduce the tumor load in a subject.
Andreas G. Moraitis
Filed: 17 Jun 18
Utility
Concomitant Administration of Glucocorticoid Receptor Modulators and CYP3A Inhibitors
13 May 20
Applicant provides methods of treating diseases including Cushing's syndrome and hormone-sensitive cancers by concomitant administration of a glucocorticoid receptor modulator (GRM) and steroidogenesis inhibitors, and by concomitant administration of a GRM and CYP3A inhibitors.
Joseph K. Belanoff
Filed: 27 Feb 18
Utility
Glucocorticoid receptor modulators to treat pancreatic cancer
11 May 20
Hazel Hunt, Thaddeus S. Block
Filed: 22 Aug 19
Utility
Use of glucocorticoid receptor antagonists in combination with glucocorticoids to treat adrenal insufficiency
6 Apr 20
This invention provides for a method of treating secondary adrenal insufficiency by co-administrating therapeutically effective amounts of a glucocorticoid and a glucocorticoid receptor antagonist to the patient in need thereof.
Andreas G. Moraitis, Pejman Cohan, Joseph K. Belanoff
Filed: 29 Mar 16
Utility
Methods for diagnosing and assessing treatment for Cushing's syndrome
30 Mar 20
Methods are provided for assessing a clinical response to a glucocorticoid receptor antagonist (GRA) in a human subject and for diagnosing Cushing's syndrome.
Joseph K. Belanoff, Hazel Hunt, John Francis Unitt, Andreas G. Moraitis
Filed: 17 May 16
Utility
Method for Differentially Diagnosing Acth-dependent Cushing's Syndrome
18 Mar 20
This invention provides for an improved method for differentially diagnosing ACTH-dependent Cushing's syndrome.
Andres G. Moraitis
Filed: 20 Nov 19
Utility
Glucocorticoid receptor modulators to treat cervical cancer
24 Feb 20
Methods for treating a subject having a cancerous tumor are disclosed.
Hazel Hunt
Filed: 8 Nov 18
Utility
Optimizing Mifepristone Absorption
8 Jan 20
The present invention provides a method for altering the pharmacokinetics of mifepristone upon oral administration.
Joe Belanoff, Robert Roe, Caroline Loewy
Filed: 17 Sep 19
Utility
Heteroaryl-ketone Fused Azadecalin Glucocorticoid Receptor Modulators
8 Jan 20
The present invention provides heteroaryl ketone fused azadecalin compounds and methods of using the compounds as glucocorticoid receptor modulators.
Hazel Hunt, Tony Johnson, Nicholas Ray, Iain Walters
Filed: 12 Sep 19
Utility
Glucocorticoid Receptor Modulators to Treat Pancreatic Cancer
1 Jan 20
Hazel Hunt, Thaddeus S. Block
Filed: 22 Aug 19
Utility
Use of Acth In Assessment and Prophylactic Treatment of Hypokalemia Associated with Glucocorticoid Receptor Modulator Treatment of Cushing's Syndrome Patients
1 Jan 20
This invention provides new methods for a) identifying Cushing's Syndrome patients at high risk of developing hypokalemia during glucocorticoid receptor modulator (GRM) treatment, and b) for prophylactically treating such patients to prevent, or reduce the severity of, hypokalemia.
Andreas Moraitis
Filed: 29 Apr 19
Utility
Use of Cortisol in Assessment and Prophylactic Treatment of Hypokalemia Associated with Glucocorticoid Receptor Modulator Treatment of Cushing's Syndrome Patients
1 Jan 20
This invention provides new methods for a) identifying Cushing's Syndrome patients at high risk of developing hypokalemia during glucocorticoid receptor modulator (GRM) treatment, and b) for prophylactically treating such patients to prevent, or reduce the severity of, hypokalemia.
Andreas Moraitis
Filed: 21 Aug 18
Utility
Optimizing mifepristone absorption
9 Dec 19
The present invention provides a method for altering the pharmacokinetics of mifepristone upon oral administration.
Joe Belanoff, Robert Roe, Caroline Loewy
Filed: 14 Nov 12
Utility
Methods of preparing regioselective N-alkyl triazoles
2 Dec 19
Hazel Hunt, Arjen Christiaan Breman, Bas Wilhelmus Theodorus Gruijters
Filed: 21 Apr 19
Utility
Method for differentially diagnosing ACTH-dependent Cushing's syndrome
2 Dec 19
This invention provides for an improved method for differentially diagnosing ACTH-dependent Cushing's syndrome.
Andreas G. Moraitis
Filed: 22 May 18
Utility
Heteroaryl-ketone fused azadecalin glucocorticoid receptor modulators
28 Oct 19
The present invention provides heteroaryl ketone fused azadecalin compounds and methods of using the compounds as glucocorticoid receptor modulators.
Hazel Hunt, Tony Johnson, Nicholas Ray, Iain Walters
Filed: 5 Feb 18
Utility
Methods of Preparing Regioselective N-alkyl Triazoles
23 Oct 19
Hazel Hunt, Arjen Christiaan Breman, Bas Wilhelmus Theodorus Gruijters
Filed: 21 Apr 19