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MRNA Moderna

Moderna is an American, Cambridge, Massachusetts-based biotechnology company focused on drug discovery, drug development, and vaccine technologies based exclusively on messenger RNA . The Moderna technology platform is to insert synthetic mRNA into living cells that would reprogram the cells to develop immune responses, rather than being created externally and injected as with conventional medicines. It is a novel technique abandoned by several large pharmaceutical and biotechnology companies that were unable to overcome the side effects of inserting RNA into cells. As of May 2020, no mRNA drug has been approved for human use.

Company profile

Ticker
MRNA, 0A45
Exchange
CEO
Stephane Bancel
Employees
Incorporated
Location
Fiscal year end
Former names
Moderna Therapeutics, Inc.
SEC CIK
IRS number
813467528

MRNA stock data

(
)

Investment data

Data from SEC filings
Securities sold
Number of investors

Calendar

6 May 21
18 May 21
31 Dec 21
Quarter (USD)
Mar 21 Dec 20 Sep 20 Jun 20
Revenue
Cost of revenue
Operating income
Operating margin
Net income
Net profit margin
Cash on hand
Change in cash
Diluted EPS
Annual (USD)
Dec 20 Dec 19 Dec 18
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Cost of revenue
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Diluted EPS

Financial data from Moderna earnings reports.

Date Owner Security Transaction Code Indirect 10b5-1 $Price #Shares $Value #Remaining
13 May 21 Lori M. Henderson Common Stock Sell Dispose S No Yes 152.6 6,600 1.01M 901
13 May 21 Lori M. Henderson Common Stock Option exercise Aquire M No Yes 14.85 6,600 98.01K 7,501
13 May 21 Lori M. Henderson Stock Option Common Stock Option exercise Dispose M No Yes 14.85 6,600 98.01K 354,752
13 May 21 Stephen Hoge Common Stock Sell Dispose S No Yes 152.6 15,000 2.29M 1,609,597
13 May 21 Stephen Hoge Common Stock Option exercise Aquire M No Yes 0 10,000 0 1,624,597
13 May 21 Stephen Hoge Common Stock Option exercise Aquire M No Yes 10.9 5,000 54.5K 1,614,597
13 May 21 Stephen Hoge Stock Option Common Stock Option exercise Dispose M No Yes 0 10,000 0 487,431
13 May 21 Stephen Hoge Stock Option Common Stock Option exercise Dispose M No Yes 10.9 5,000 54.5K 316,972
13 May 21 Bancel Stephane Common Stock Sell Dispose S Yes Yes 152.6 10,000 1.53M 7,414,880
12 May 21 Tal Zvi Zaks Common Stock Sell Dispose S No Yes 154.11 5,000 770.55K 0

Data for the last complete 13F reporting period. To see the most recent changes to ownership, click the ownership history button above.

59.6% owned by funds/institutions
13F holders
Current Prev Q Change
Total holders 704 535 +31.6%
Opened positions 230 140 +64.3%
Closed positions 61 81 -24.7%
Increased positions 219 207 +5.8%
Reduced positions 178 130 +36.9%
13F shares
Current Prev Q Change
Total value 25.13B 14.32B +75.4%
Total shares 239.32M 202.58M +18.1%
Total puts 16.31M 9.99M +63.3%
Total calls 12.2M 45.92M -73.4%
Total put/call ratio 1.3 0.2 +514.4%
Largest owners
Shares Value Change
Flagship Pioneering 30.87M $3.23B 0.0%
Flagship Ventures Fund IV General Partner 30.87M $3.22B NEW
Baillie Gifford & Co 24.31M $2.54B +236.5%
Vanguard 23.37M $2.44B -16.2%
BLK Blackrock 20.48M $2.14B +1.2%
Bancel Stephane 9.05M $945.49M NEW
FMR 7.95M $830.09M -76.8%
STT State Street 6.02M $629.4M -8.5%
MS Morgan Stanley 5.8M $605.41M +15.1%
Theleme Partners 5.34M $558.26M -30.2%
Largest transactions
Shares Bought/sold Change
Flagship Ventures Fund IV General Partner 30.87M +30.87M NEW
FMR 7.95M -26.28M -76.8%
Baillie Gifford & Co 24.31M +17.09M +236.5%
Bancel Stephane 9.05M +9.05M NEW
Vanguard 23.37M -4.5M -16.2%
D. E. Shaw & Co. 3.11M +2.34M +305.9%
Theleme Partners 5.34M -2.31M -30.2%
Norges Bank 2.31M +2.31M NEW
Renaissance Technologies 1.75M +1.75M NEW
Citadel Advisors 1.08M +1.07M +6505.7%

Financial report summary

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Management Discussion
  • We brought five new development candidates forward in 2020: a COVID-19 vaccine (mRNA-1273); interleukin-2 (IL-2); programmed death-ligand 1 (PD-L1); a pediatric Respiratory Syncytial Virus (RSV) vaccine; and an Epstein-Barr Virus (EBV) vaccine, as part of our mission to use our technology to advance global public health.
  • In response to the global coronavirus pandemic, we are pursuing the rapid development and manufacture of our mRNA-1273 vaccine, for the treatment of SARS-CoV-2, the novel strain of coronavirus that causes COVID-19, in collaboration with the Vaccine Research Center and Division of Microbiology and Infectious Diseases of the National Institute of Allergy and Infectious Diseases, or NIAID, part of the National Institutes of Health, or NIH. The progress of mRNA-1273 during 2020 has resulted in the need for us to devote significant resources toward the development and manufacture of this product. Significant capital investment is necessary for ongoing clinical development, manufacturing and distribution of the COVID-19 vaccine at a scale necessary to meet demand in a global pandemic environment. This capital investment includes the ongoing clinical development for updated versions of the COVID-19 vaccine that may provide continued protection against variants of the SARS-CoV-2 virus. BARDA has committed to fund up to $954.9 million to accelerate the clinical development and manufacturing process scale-up of our COVID-19 vaccine. Under the terms of the agreement, BARDA will fund the advancement of mRNA-1273 to FDA licensure and the scale-up of manufacturing processes. The agreement does not contemplate any product stockpiling.
  • In February and May 2020, we completed two separate public equity offerings, resulting in aggregate net proceeds of $1.85 billion, net of underwriting discounts, commissions and offering expenses. This additional funding has enabled us to substantially expand our manufacturing network, purchase the required capital equipment, hire appropriate global staff and secure the raw materials and other consumables to manufacture substantial doses of our COVID-19 vaccine.
Content analysis
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Patents

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Polynucleotides encoding interleukin-12 (IL12) and uses thereof
11 May 21
The present disclosure relates to polynucleotides comprising an open reading frame of linked nucleosides encoding human interleukin-12 (IL12), functional fragments thereof, and fusion proteins comprising IL12.
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Polynucleotides encoding galactose-1-phosphate uridylyltransferase for the treatment of galactosemia type 1
11 May 21
The invention relates to mRNA therapy for the treatment of galactosemia type 1 (Gal-1). mRNAs for use in the invention, when administered in vivo, encode human galactose-1-phosphate uridylyltransferase (GALT), isoforms thereof, functional fragments thereof, and fusion proteins comprising GALT. mRNAs of the invention are preferably encapsulated in lipid nanoparticles (LNPs) to effect efficient delivery to cells and/or tissues in subjects, when administered thereto. mRNA therapies of the invention increase and/or restore deficient levels of GALT expression and/or activity in subjects. mRNA therapies of the invention further decrease levels of toxic metabolites associated with deficient GALT activity in subjects, namely galactose-1-phosphate (Gal-1-P).
GRANT
Utility
Methods of using OX40 ligand encoding polynucleotides
11 May 21
The disclosure relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotide molecules comprising an mRNA encoding an OX40L polypeptide.
APP
Utility
Immunomodulatory Therapeutic Mrna Compositions Encoding Activating Oncogene Mutation Peptides
6 May 21
The disclosure features immunomodulatory therapeutic compositions of an mRNA encoding an activating oncogene mutation peptide and an mRNA encoding a polypeptide that enhances immune responses to the activating oncogene mutation peptide, for example an mRNA encoding an immune potentiator.